Assay Detail
Functional
CHEMBL617001
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for its antagonist affinity towards 5-hydroxytryptamine 1B receptor of guinea pig
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Histaprodifens: synthesis, pharmacological in vitro evaluation, and molecular modeling of a new class of highly active and selective histamine H(1)-receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.97 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275035 | — | — | 1 | 5.09 |
| CHEMBL275507 | — | — | 1 | 4.85 |
| CHEMBL11553 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275035 | — | Kd | = | 8128.31 | nM | 5.09 |
| CHEMBL275507 | — | Kd | = | 14125.38 | nM | 4.85 |
| CHEMBL11553 | — | Kd | > | 31622.78 | nM | - |