Assay Detail
Functional
CHEMBL617064
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Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]DOI radioligand
5
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.20 | 6.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL319415 | — | — | 1 | 6.67 |
| CHEMBL316527 | — | — | 1 | 6.47 |
| CHEMBL102347 | — | — | 2 | 6.43 |
| CHEMBL26687 | MESCALINE | 1.0 | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL319415 | — | Ki | = | 215.6 | nM | 6.67 |
| CHEMBL316527 | — | Ki | = | 335.0 | nM | 6.47 |
| CHEMBL102347 | — | Ki | = | 368.4 | nM | 6.43 |
| CHEMBL26687 | MESCALINE | Ki | = | 551.0 | nM | 6.26 |
| CHEMBL102347 | — | Ki | = | 6405.0 | nM | 5.19 |