Assay Detail
Binding
CHEMBL617071
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding ability of compound at cloned human 5-hydroxytryptamine 2A receptor using [125 I]DOI as radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.43 | 9.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305275 | — | — | 1 | 9.32 |
| CHEMBL445106 | — | — | 1 | 7.89 |
| CHEMBL307770 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305275 | — | Ki | = | 0.48 | nM | 9.32 |
| CHEMBL445106 | — | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL307770 | — | Ki | = | 8500.0 | nM | 5.07 |