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Assay Detail

CHEMBL617076

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound to human 5-hydroxytryptamine 2A receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A new class of selective and potent inhibitors of neuronal nitric oxide synthase.
Lowe JA, Qian W, Volkmann RA, Heck S, Nowakowski J, Nelson R, Nolan C, Liston D, Ward K, Zorn S, Johnson C, Vanase M, Faraci WS, Verdries KA, Baxter J, Doran S, Sanders M, Ashton M, Whittle P, Stefaniak M.
Bioorg Med Chem Lett (1999) 9 : 2569 -2572
PubMed 10498210 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.85 7.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL87187 1 7.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL87187 Ki = 14.0 nM 7.85