Assay Detail
Binding
CHEMBL617087
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Binding affinity was measured on 5-hydroxytryptamine 2A receptor in GF6 cells transfected with human 5-HT2A gene labeled with [3H]ketanserin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | GF6 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
5-(Nonyloxy)tryptamine: a novel high-affinity 5-HT1D beta serotonin receptor agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.44 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97450 | — | — | 1 | 6.58 |
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 6.29 |
| CHEMBL128 | SUMATRIPTAN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97450 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL39 | SEROTONIN | Ki | = | 510.0 | nM | 6.29 |
| CHEMBL128 | SUMATRIPTAN | Ki | > | 1000.0 | nM | - |