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Assay Detail

CHEMBL617187

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the binding affinity at 5- HT2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL3446)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

The serotonin 5-HT4 receptor. 1. Design of a new class of agonists and receptor map of the agonist recognition site.
Buchheit KH, Gamse R, Giger R, Hoyer D, Klein F, Klöppner E, Pfannkuche HJ, Mattes H.
J Med Chem (1995) 38 : 2326 -2330
PubMed 7608898 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.14 8.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1729 CISAPRIDE 4.0 1 8.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1729 CISAPRIDE Ki = 7.2 nM 8.14