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Assay Detail

CHEMBL617202

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards 5-HT7 receptor by the displacement of [3H]-5-CT] in human recombinant receptors in mammalian cell
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 7 (CHEMBL3155)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New tetrahydrobenzindoles as potent and selective 5-HT(7) antagonists with increased In vitro metabolic stability.
Kikuchi C, Suzuki H, Hiranuma T, Koyama M.
Bioorg Med Chem Lett (2003) 13 : 61 -64
PubMed 12467617 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.14 8.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL348890 1 8.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL348890 Ki = 7.244 nM 8.14