Assay Detail
Binding
CHEMBL617256
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Binding affinity against 5-hydroxytryptamine 2A receptor human cloned receptors in HEK 293 cells using [3H]ketanserin as radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel ergot alkaloid as a 5-HT(1A) inhibitor produced by Dicyma sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.70 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 6.40 |
| CHEMBL146942 | — | — | 1 | 5.00 |
| CHEMBL18840 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39 | SEROTONIN | Ki | = | 398.11 | nM | 6.40 |
| CHEMBL146942 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL18840 | — | Ki | < | 5011.87 | nM | - |