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Assay Detail

CHEMBL617290

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for binding affinity towards human 5-hydroxytryptamine 2C receptor using [3H]5-HT as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2C (CHEMBL225)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.
Chang-Fong J, Addo J, Dukat M, Smith C, Mitchell NA, Herrick-Davis K, Teitler M, Glennon RA.
Bioorg Med Chem Lett (2002) 12 : 155 -158
PubMed 11755343 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.42 8.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL40726 1 8.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL40726 Ki = 3.8 nM 8.42