Assay Detail
Functional
CHEMBL617350
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for its inverse agonist activity against 5-hydroxytryptamine 2A receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Multistep solution-phase parallel synthesis of spiperone analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.17 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL79834 | SPIRAMIDE | 2.0 | 1 | 9.50 |
| CHEMBL81377 | — | — | 1 | 7.90 |
| CHEMBL80093 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL79834 | SPIRAMIDE | IC50 | = | 0.3162 | nM | 9.50 |
| CHEMBL81377 | — | IC50 | = | 12.59 | nM | 7.90 |
| CHEMBL80093 | — | IC50 | = | 79.43 | nM | 7.10 |