Assay Detail
Binding
CHEMBL617357
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ketanserin binding to 5-hydroxytryptamine 2A receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.76 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL138458 | — | — | 1 | 6.34 |
| CHEMBL141209 | — | — | 1 | 5.18 |
| CHEMBL138809 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL138458 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL141209 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL138809 | — | IC50 | > | 10000.0 | nM | - |