Assay Detail
Binding
CHEMBL617429
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Compound was evaluated for binding affinity against 5-hydroxytryptamine 2 receptor from rat
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Serotonin 2 (5-HT2) receptor (CHEMBL2093870) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.78 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL419505 | — | — | 1 | 6.90 |
| CHEMBL300780 | — | — | 1 | 6.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL419505 | — | Ki | = | 125.0 | nM | 6.90 |
| CHEMBL300780 | — | Ki | = | 223.0 | nM | 6.65 |