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Assay Detail

CHEMBL617671

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory constant against 5-hydroxytryptamine 2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Serotonin 2 (5-HT2) receptor (CHEMBL2093870)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Ketanserin analogues: structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding.
Herndon JL, Ismaiel A, Ingher SP, Teitler M, Glennon RA.
J Med Chem (1992) 35 : 4903 -4910
PubMed 1479590 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.90 7.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL18972 GLEMANSERIN 2.0 1 7.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL18972 GLEMANSERIN Ki = 12.5 nM 7.90