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Assay Detail

CHEMBL617680

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Binding
Tested for its binding affinity to Tested for its binding affinity to 5-hydroxytryptamine 2 receptor using [3H]-ketanserin radioligand assay using [3H]-ketanserin radioligand assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin 2 (5-HT2) receptor (CHEMBL2093870)
Type PROTEIN FAMILY
Organism Rattus norvegicus

Publication

Synthesis and serotonin receptor binding properties of 5-substituted 3-(1,2,5,6-tetrahydropyridin-3-yl) indoles
Dahlgren T, Dean R, Gharat L, Johansson A, Lambert G, Li H, Nelson D, Yang Y, Martin A
Bioorg Med Chem Lett (1995) 5 : 2963 -2968
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.04 6.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL18785 RU-24969 1 6.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL18785 RU-24969 Ki = 912.0 nM 6.04