Assay Detail
Binding
CHEMBL617759
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Binding constant towards serotonin receptor subtype 5-hydroxytryptamine 2C receptor expressed in 3T3 cells using [3H]5-HT as radioligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | NIH3T3 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.69 | 7.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24474 | — | — | 1 | 7.69 |
| CHEMBL23575 | — | — | 1 | - |
| CHEMBL23038 | — | — | 1 | - |
| CHEMBL542806 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24474 | — | Ki | = | 20.42 | nM | 7.69 |
| CHEMBL23575 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL23038 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL542806 | — | Ki | < | 10000.0 | nM | - |