Assay Detail
Binding
CHEMBL617765
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Inhibitory constant on human 5-hydroxytryptamine 2C receptor transfected in to HeLa cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HeLa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.81 | 7.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL333174 | — | — | 1 | 7.56 |
| CHEMBL164471 | — | — | 1 | 7.46 |
| CHEMBL143027 | — | — | 1 | 5.40 |
| CHEMBL95098 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL333174 | — | Ki | = | 27.54 | nM | 7.56 |
| CHEMBL164471 | — | Ki | = | 34.67 | nM | 7.46 |
| CHEMBL143027 | — | Ki | = | 3981.07 | nM | 5.40 |
| CHEMBL95098 | — | Ki | < | 10000.0 | nM | - |