Assay Detail
Binding
CHEMBL617887
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Inhibition of human 5-hydroxytryptamine 2C receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
From hit to lead. Analyzing structure-profile relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.81 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL325674 | — | — | 1 | 6.46 |
| CHEMBL326538 | — | — | 1 | 6.19 |
| CHEMBL113956 | — | — | 1 | 5.85 |
| CHEMBL115076 | — | — | 1 | 5.74 |
| CHEMBL116463 | — | — | 1 | 5.56 |
| CHEMBL325516 | — | — | 1 | 5.46 |
| CHEMBL117537 | — | — | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL325674 | — | IC50 | = | 345.0 | nM | 6.46 |
| CHEMBL326538 | — | IC50 | = | 652.0 | nM | 6.19 |
| CHEMBL113956 | — | IC50 | = | 1420.0 | nM | 5.85 |
| CHEMBL115076 | — | IC50 | = | 1830.0 | nM | 5.74 |
| CHEMBL116463 | — | IC50 | = | 2760.0 | nM | 5.56 |
| CHEMBL325516 | — | IC50 | = | 3450.0 | nM | 5.46 |
| CHEMBL117537 | — | IC50 | = | 4070.0 | nM | 5.39 |