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Assay Detail

CHEMBL618079

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards murine 5-hydroxytryptamine 5A receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

5-hydroxytryptamine receptor 5A (CHEMBL3597)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Glennon RA.
J Med Chem (2003) 46 : 2795 -2812
PubMed 12825922 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.67 6.67

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL266250 1 6.67
CHEMBL92879 1 5.28
CHEMBL478 CHLOROPHENYLPIPERAZINE 2.0 1 5.06
CHEMBL18772 QUIPAZINE 2.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL266250 Ki = 215.0 nM 6.67
CHEMBL92879 Ki = 5300.0 nM 5.28
CHEMBL478 CHLOROPHENYLPIPERAZINE Ki = 8700.0 nM 5.06
CHEMBL18772 QUIPAZINE Ki > 10000.0 nM -