Assay Detail
Binding
CHEMBL618096
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards human 5-hydroxytryptamine 6 receptor was evaluated using [125I]-2-iodo LSD as radioligand
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.71 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274384 | — | — | 1 | 7.77 |
| CHEMBL277120 | — | — | 1 | 6.98 |
| CHEMBL97518 | — | — | 1 | 6.75 |
| CHEMBL266591 | — | — | 1 | 6.40 |
| CHEMBL478 | CHLOROPHENYLPIPERAZINE | 2.0 | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274384 | — | Ki | = | 17.0 | nM | 7.77 |
| CHEMBL277120 | — | Ki | = | 104.0 | nM | 6.98 |
| CHEMBL97518 | — | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL266591 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL478 | CHLOROPHENYLPIPERAZINE | Ki | = | 2300.0 | nM | 5.64 |