Assay Detail
Binding
CHEMBL618121
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Binding affinity towards human 5-hydroxytryptamine 6 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Binding of beta-carbolines at 5-HT(2) serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.79 | 5.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295234 | — | — | 1 | 5.84 |
| CHEMBL269538 | HARMINE | 1.0 | 1 | 5.83 |
| CHEMBL338115 | — | — | 1 | 5.71 |
| CHEMBL6310 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295234 | — | Ki | = | 1450.0 | nM | 5.84 |
| CHEMBL269538 | HARMINE | Ki | = | 1480.0 | nM | 5.83 |
| CHEMBL338115 | — | Ki | = | 1930.0 | nM | 5.71 |
| CHEMBL6310 | — | Ki | > | 10000.0 | nM | - |