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Assay Detail

CHEMBL618139

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested against 5-hydroxytryptamine 3 receptor in experiment 1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin 3 (5-HT3) receptor (CHEMBL2094132)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide.
Gaster LM, Jennings AJ, Joiner GF, King FD, Mulholland KR, Rahman SK, Starr S, Wyman PA, Wardle KA, Ellis ES.
J Med Chem (1993) 36 : 4121 -4123
PubMed 8258837 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL68131 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL68131 Ki = 251.19 nM 6.60