Assay Detail
Binding
CHEMBL618164
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Binding affinity against 5-hydroxytryptamine 7 human receptors
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel ergot alkaloid as a 5-HT(1A) inhibitor produced by Dicyma sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.56 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18840 | — | — | 1 | 9.40 |
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 8.50 |
| CHEMBL146942 | — | — | 1 | 8.50 |
| CHEMBL2112882 | — | — | 1 | 8.20 |
| CHEMBL263881 | LYSERGIDE | 2.0 | 1 | 8.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18840 | — | Ki | = | 0.3981 | nM | 9.40 |
| CHEMBL39 | SEROTONIN | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL146942 | — | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL2112882 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL263881 | LYSERGIDE | Ki | = | 6.31 | nM | 8.20 |