Assay Detail
Binding
CHEMBL619170
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to produce half-maximal response against 5-hydroxytryptamine receptor on the L-type calcium current (I Ca) in isolated human atrial myocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Cardiac atrium |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New arylpiperazine derivatives as antagonists of the human cloned 5-HT(4) receptor isoforms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.35 | 8.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121913 | — | — | 1 | 8.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121913 | — | EC50 | = | 4.5 | nM | 8.35 |