Assay Detail
Functional
CHEMBL620364
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Inhibitory concentration against 8226/Dox40 (Dox-Re) cancer cell line
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RPMI-8226 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.01 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320647 | — | — | 1 | 7.52 |
| CHEMBL101871 | — | — | 1 | 7.30 |
| CHEMBL369474 | PSOROSPERMIN | — | 1 | 6.64 |
| CHEMBL101299 | — | — | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320647 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL101871 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL369474 | PSOROSPERMIN | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL101299 | — | IC50 | = | 270.0 | nM | 6.57 |