Assay Detail
Functional
CHEMBL620425
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Cytotoxicity against human lung carcinoma A549 cell line using MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antitumor activity of 4-phenyl-1-arylsulfonyl imidazolidinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.66 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39830 | — | — | 1 | 6.70 |
| CHEMBL39033 | — | — | 1 | 6.36 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.70 |
| CHEMBL38709 | — | — | 1 | 5.46 |
| CHEMBL289615 | — | — | 1 | 5.32 |
| CHEMBL7643 | SULOFENUR | 2.0 | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39830 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL39033 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1990.0 | nM | 5.70 |
| CHEMBL38709 | — | IC50 | = | 3450.0 | nM | 5.46 |
| CHEMBL289615 | — | IC50 | = | 4740.0 | nM | 5.32 |
| CHEMBL7643 | SULOFENUR | IC50 | = | 36430.0 | nM | 4.44 |