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Assay Detail

CHEMBL620609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for 5-hydroxytryptamine 4 receptor antagonist activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 4 (CHEMBL1875)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

5-HT4 receptor ligands: applications and new prospects.
Langlois M, Fischmeister R.
J Med Chem (2003) 46 : 319 -344
PubMed 12540230 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.61 8.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL97019 1 8.17
CHEMBL99591 1 7.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL97019 Ki = 6.7 nM 8.17
CHEMBL99591 Ki = 91.9 nM 7.04