Assay Detail

CHEMBL620612

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Binding

Tested for 5-hydroxytryptamine 4 binding affinity against cisapride

ChEMBL ↗

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Target

5-hydroxytryptamine receptor 4 (CHEMBL1875) ↗

Open DB target context

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5-hydroxytryptamine receptor 4 (CHEMBL1875) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target 5-hydroxytryptamine receptor 4

CHEMBL1875

Anchored from Assay target.

Protein identity 5-hydroxytryptamine receptor 4

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

5-hydroxytryptamine receptor 4 (CHEMBL1875) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

5-HT4 receptor ligands: applications and new prospects.

Langlois M, Fischmeister R.
J Med Chem (2003) 46 : 319 -344
PubMed 12540230 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	7.14	7.14

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL15585	BRL-20627	—	1	7.14
CHEMBL301039	—	—	1	7.14

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL15585	BRL-20627	EC50	=	72.44	nM	7.14
CHEMBL301039	—	EC50	=	72.44	nM	7.14