Assay Detail
Functional
CHEMBL620798
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity towards 5-hydroxytryptamine 6 receptor was evaluated in cAMP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.31 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL328816 | — | — | 1 | 6.52 |
| CHEMBL94422 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL328816 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL94422 | — | IC50 | = | 800.0 | nM | 6.10 |