Assay Detail

CHEMBL620803

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antagonistic activity towards 5-hydroxytryptamine 6 receptor

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

5-hydroxytryptamine receptor 6 (CHEMBL3371) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

5-hydroxytryptamine receptor 6 (CHEMBL3371) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target 5-hydroxytryptamine receptor 6

CHEMBL3371

Anchored from Assay target.

Protein identity 5-hydroxytryptamine receptor 6

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	8 — Homologous single protein target
Curated By	Expert

Target

5-hydroxytryptamine receptor 6 (CHEMBL3371) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).

Glennon RA.
J Med Chem (2003) 46 : 2795 -2812
PubMed 12825922 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	8.88	8.88

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL76237	—	—	1	8.88

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL76237	—	Kd	=	1.318	nM	8.88