Assay Detail
Binding
CHEMBL620829
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Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.06 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL42 | CLOZAPINE | 4.0 | 1 | 8.05 |
| CHEMBL7143 | — | — | 1 | 6.84 |
| CHEMBL7318 | — | — | 1 | 6.81 |
| CHEMBL267615 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL42 | CLOZAPINE | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL7143 | — | Ki | = | 145.0 | nM | 6.84 |
| CHEMBL7318 | — | Ki | = | 155.0 | nM | 6.81 |
| CHEMBL267615 | — | Ki | = | 300.0 | nM | 6.52 |