Assay Detail
Functional
CHEMBL621436
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Compound was tested for potency against human lung A549 cells using sulforhodamine B assay.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1,4-disubstituted anthracene antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.38 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | 3.0 | 1 | 7.77 |
| CHEMBL125332 | — | — | 1 | 6.15 |
| CHEMBL287188 | — | — | 1 | 5.30 |
| CHEMBL22696 | — | — | 1 | 5.30 |
| CHEMBL125698 | — | — | 1 | 5.09 |
| CHEMBL332153 | — | — | 1 | 4.04 |
| CHEMBL121864 | — | — | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL125332 | — | IC50 | = | 710.0 | nM | 6.15 |
| CHEMBL287188 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL22696 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL125698 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL332153 | — | IC50 | = | 91000.0 | nM | 4.04 |
| CHEMBL121864 | — | IC50 | = | 99000.0 | nM | 4.00 |