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Assay Detail

CHEMBL622724

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for the in vitro cytotoxicity against transformed chinese hamster fibroblast line AA8
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO-AA8
Confidence 1 — Organism
Curated By Intermediate

Target

CHO-AA8 (CHEMBL614555)
Type CELL-LINE
Organism Cricetulus griseus

Publication

DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
Gourdie TA, Valu KK, Gravatt GL, Boritzki TJ, Baguley BC, Wakelin LP, Wilson WR, Woodgate PD, Denny WA.
J Med Chem (1990) 33 : 1177 -1186
PubMed 2319563 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL277152 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL277152 IC50 = 570.0 nM 6.24