Assay Detail
Functional
CHEMBL622732
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for in vitro cytotoxicities against Chinese hamster ovary derived AA8 cell lines.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO-AA8 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of DNA-targeted spatially separated bis(aniline mustards) as potential alkylating agents with enhanced DNA cross-linking capability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.06 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278918 | — | — | 1 | 5.54 |
| CHEMBL515 | CHLORAMBUCIL | 4.0 | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278918 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL515 | CHLORAMBUCIL | IC50 | = | 26000.0 | nM | 4.58 |