Assay Detail
Physicochemical
CHEMBL629637
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Dissociation constant of the Compound
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 7.57 | 8.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66462 | — | — | 1 | 8.29 |
| CHEMBL41934 | — | — | 1 | 7.76 |
| CHEMBL305798 | — | — | 1 | 7.68 |
| CHEMBL432911 | — | — | 1 | 7.50 |
| CHEMBL63804 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66462 | — | Kd | = | 5.1 | nM | 8.29 |
| CHEMBL41934 | — | Kd | = | 17.5 | nM | 7.76 |
| CHEMBL305798 | — | Kd | = | 21.0 | nM | 7.68 |
| CHEMBL432911 | — | Kd | = | 32.0 | nM | 7.50 |
| CHEMBL63804 | — | Kd | = | 240.0 | nM | 6.62 |