Assay Detail
Functional
CHEMBL639914
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Stimulation of endometrial activity in Ishikawa human endometrial adenocarcinoma cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Ishikawa |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and pharmacology of a novel pyrrolo[2,1,5-cd] indolizine (NNC 45-0095), a high affinity non-steroidal agonist for the estrogen receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.95 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1628161 | MOXESTROL | 2.0 | 1 | 10.00 |
| CHEMBL420017 | — | — | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1628161 | MOXESTROL | EC50 | = | 0.1 | nM | 10.00 |
| CHEMBL420017 | — | EC50 | = | 13.0 | nM | 7.89 |