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Assay Detail

CHEMBL640457

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for the inhibitory constant for adenosine deaminase (ADA)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Adenosine deaminase (CHEMBL3206)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Synthesis of pyrimidin-2-one nucleosides as acid-stable inhibitors of cytidine deaminase.
Kim CH, Marquez VE, Mao DT, Haines DR, McCormack JJ.
J Med Chem (1986) 29 : 1374 -1380
PubMed 3735306 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL504567 ZEBULARINE 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL504567 ZEBULARINE Ki = 1000.0 nM 6.00