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Assay Detail

CHEMBL640603

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for Adenosine A1 receptor using [125I]-ABA in chick cerebellar membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Cerebellum
Subcellular Membrane
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Adenosine receptor A1 (CHEMBL2114)
Type SINGLE PROTEIN
Organism Gallus gallus

Publication

N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors.
Kwatra MM, Leung E, Hosey MM, Green RD.
J Med Chem (1987) 30 : 954 -956
PubMed 3572985 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL609650 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL609650 IC50 = 11.1 nM 7.96