Assay Detail
Functional
CHEMBL641185
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Compound was tested for the inhibition of AMML (acute myelomonocytic leukemia)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | AMML |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleoside conjugates. 7. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of ether lipids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.66 | 5.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3350507 | — | — | 1 | 5.87 |
| CHEMBL3350505 | — | — | 1 | 5.64 |
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 5.64 |
| CHEMBL107514 | (R)-EDELFOSINE | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3350507 | — | IC50 | = | 1350.0 | nM | 5.87 |
| CHEMBL3350505 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL803 | CYTARABINE | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL107514 | (R)-EDELFOSINE | IC50 | = | 3300.0 | nM | 5.48 |