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Assay Detail

CHEMBL641430

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for inhibition of Adenovirus type 2 proteinase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human adenovirus 2
Confidence 1 — Organism
Curated By Intermediate

Target

Human adenovirus 2 (CHEMBL613715)
Type ORGANISM
Organism Human adenovirus 2

Publication

Inhibitors of the adenovirus type 2 proteinase based on substrate-like tetrapeptide nitriles
Cornish JA, Murray H, Kemp GD, Gani D
Bioorg Med Chem Lett (1995) 5 : 25 -30
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL100227 1 5.00
CHEMBL100223 1 -
CHEMBL100630 1 -
CHEMBL100228 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL100227 IC50 = 10000.0 nM 5.00
CHEMBL100223 IC50 = 6900000.0 nM -
CHEMBL100630 IC50 = 1800000.0 nM -
CHEMBL100228 IC50 = 400000.0 nM -