Assay Detail
Functional
CHEMBL642861
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Binding affinity on adrenal cortex microsomes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bos taurus |
| Tissue | Adrenal cortex |
| Subcellular | Microsomes |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Rapid synthesis and properties of ()-6-Deoxy-6-fluoro-myo-inositol-1,4,5-tris(phosphate) an analogue of myo-inositol-1,4,5-tris(phosphate)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.40 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | — | 1 | 8.00 |
| CHEMBL18162 | — | — | 1 | 5.80 |
| CHEMBL278700 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | Kd | = | 10.0 | nM | 8.00 |
| CHEMBL18162 | — | Kd | = | 1600.0 | nM | 5.80 |
| CHEMBL278700 | — | Kd | = | 4000.0 | nM | 5.40 |