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Assay Detail

CHEMBL643593

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Receptor binding affinity for Angiotensin II receptor, type 2 determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Type-2 angiotensin II receptor (CHEMBL257)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

1,4-substituted indoles: a potent and selective class of angiostensin II receptor antagonists
Poss MA, Gu Z, Ryono DE, Reid JA, Sieber-McMaster E, Spitzmiller ER, Dejneka T, Dickinson KE, Williams SB, Moreland S, Delaney CL, Bird J, Waldron TL, Schaeffer TR, Hedberg S, Petrillo EW
Bioorg Med Chem Lett (1994) 4 : 145 -150
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.19 5.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4524047 1 5.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4524047 Ki = 6500.0 nM 5.19