Assay Detail
Binding
CHEMBL643596
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The compound was evaluated for the inhibition of binding of [125I]-CGP 42112A to AT2 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The syntheses and binding affinities of tools for the study of angiotensin AT2 receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.24 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL170290 | — | — | 1 | 8.44 |
| CHEMBL424004 | — | — | 1 | 8.29 |
| CHEMBL265790 | — | — | 1 | 8.15 |
| CHEMBL157946 | — | — | 1 | 8.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL170290 | — | IC50 | = | 3.6 | nM | 8.44 |
| CHEMBL424004 | — | IC50 | = | 5.1 | nM | 8.29 |
| CHEMBL265790 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL157946 | — | IC50 | = | 8.3 | nM | 8.08 |