Assay Detail
Binding
CHEMBL643597
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the ability to displace 50% of totally specifically bound [125I]- Ang II from Angiotensin II receptor, type 2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Imidazolinones as nonpeptide angiotensin II receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.73 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286134 | — | — | 1 | 7.00 |
| CHEMBL39352 | — | — | 1 | 6.70 |
| CHEMBL39996 | — | — | 1 | 6.70 |
| CHEMBL36324 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286134 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL39352 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL39996 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL36324 | — | IC50 | = | 300.0 | nM | 6.52 |