Assay Detail
Functional
CHEMBL643677
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Inhibitory concentration of compound was tested as agonist activity against forskolin activated adenylate cyclase
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.39 | 7.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301060 | — | — | 3 | 7.99 |
| CHEMBL56 | 8-OH-DPAT | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301060 | — | IC50 | = | 10.2 | nM | 7.99 |
| CHEMBL301060 | — | IC50 | = | 26.3 | nM | 7.58 |
| CHEMBL301060 | — | IC50 | = | 248.0 | nM | 6.61 |
| CHEMBL56 | 8-OH-DPAT | IC50 | ~ | 8.0 | nM | - |