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Assay Detail

CHEMBL644359

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards Alpha-2 adrenergic receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Alpha-2A adrenergic receptor (CHEMBL1867)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Glennon RA.
J Med Chem (2003) 46 : 2795 -2812
PubMed 12825922 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.38 7.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL92221 1 7.72
CHEMBL27251 1 7.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL92221 Ki = 19.0 nM 7.72
CHEMBL27251 Ki = 92.8 nM 7.03