Assay Detail
Binding
CHEMBL644383
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against acetylcholinesterase as a prodrug was demonstarted
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis of 1-(2-Indolyl)pyridinium salts: a prodrug approach to acetylcholinesterase inhibition
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.65 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94 | PHYSOSTIGMINE | 3.0 | 1 | 9.00 |
| CHEMBL282887 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94 | PHYSOSTIGMINE | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL282887 | — | IC50 | = | 50000.0 | nM | 4.30 |