Assay Detail
Binding
CHEMBL644527
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Dissociation constant in high affinity sites where the binding is in 50 mM phosphate buffer for Alpha-2 adrenergic receptor
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Recognition in molecularly imprinted polymer 2-adrenoreceptor mimics
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.60 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15245 | YOHIMBINE | 3.0 | 2 | 6.92 |
| CHEMBL31410 | CORYNANTHEINE | — | 2 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15245 | YOHIMBINE | Kd | = | 120.0 | nM | 6.92 |
| CHEMBL15245 | YOHIMBINE | Kd | = | 2300.0 | nM | 5.64 |
| CHEMBL31410 | CORYNANTHEINE | Kd | = | 5600.0 | nM | 5.25 |
| CHEMBL31410 | CORYNANTHEINE | Kd | = | 25000.0 | nM | 4.60 |