Assay Detail
Binding
CHEMBL644751
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition against Aminopeptidase P from human platelets.
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.41 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2369858 | — | — | 1 | 5.96 |
| CHEMBL2369868 | — | — | 1 | 5.92 |
| CHEMBL311925 | — | — | 1 | 5.24 |
| CHEMBL78505 | — | — | 1 | 5.17 |
| CHEMBL311875 | — | — | 1 | 4.75 |
| CHEMBL78699 | — | — | 1 | - |
| CHEMBL2369857 | — | — | 1 | - |
| CHEMBL81423 | — | — | 1 | - |
| CHEMBL309274 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2369858 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2369868 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL311925 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL78505 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL311875 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL78699 | — | IC50 | = | 250000.0 | nM | - |
| CHEMBL2369857 | — | IC50 | > | 2000000.0 | nM | - |
| CHEMBL81423 | — | IC50 | > | 1500000.0 | nM | - |
| CHEMBL309274 | — | IC50 | > | 800000.0 | nM | - |