Assay Detail
Binding
CHEMBL645059
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Ability to inhibit calf intestinal adenosine deaminase (ADA); No data
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of adenosine deaminase. Studies in combining high-affinity enzyme-binding structural units. erythro-1,6-Dihydro-6-(hydroxymethyl)-9-(2-hydroxy-3-nonyl)purine and erythro-9-(2-hydroxy-3-nonyl)purine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.66 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50378 | EHNA | — | 1 | 8.89 |
| CHEMBL157495 | — | — | 1 | 6.16 |
| CHEMBL157130 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50378 | EHNA | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL157495 | — | Ki | = | 700.0 | nM | 6.16 |
| CHEMBL157130 | — | Ki | = | 12000.0 | nM | 4.92 |