Assay Detail
Binding
CHEMBL645203
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro functional activity at Alpha-1D adrenergic receptor in rat aorta
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Aorta |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.41 | 10.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL268758 | A-119637 | — | 1 | 10.60 |
| CHEMBL13647 | BMY-7378 | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL268758 | A-119637 | Kd | = | 0.02512 | nM | 10.60 |
| CHEMBL13647 | BMY-7378 | Kd | = | 6.026 | nM | 8.22 |